7 results
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
• Metabolic acidosis ... Hyperkalemia and renal ... PRIS #Diagnosis #Management ... #Pharmacology # ... Toxicity #Toxicology
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
Respiratory Distress Syndrome ... cardiac arrest Neurologic ... Metabolic: Metabolic acidosis ... hyperglycemia Other: Renal ... Toxicology #Phases #Pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... (PRIS) - acidosis ... , bradycardia. renal ... glycol (solvent) toxicity ... CriticalCare #diagnosis #management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... irrigation • Management ... nocturnal enuresis • Prevention ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
(PRES) Overview ... Immunosuppressive agents, Renal ... Medication/Drug toxicity ... #diagnosis #management ... #neurology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Overview Epidemiology ... Distal (Type I) renal ... tubular acidosis ... lubricants • Pharmacologic ... Rheumatology #Diagnosis #Management
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Overview What ... • Hypokalemia (renal ... , Renal tubular ... acidosis (RTA)) ... #management #pathophysiology