9 results
Cerebral Toxoplasmosis 
- Most comrnon CNS infection in patients with AIDS 
who are not receiving appropriate
- Most comrnon CNS ... infection in patients ... with AIDS who ... prophylaxis Clinical ... Altered mental status
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV / AIDS - Differential ... should be based on clinical ... altered mental status ... Infections in HIV
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
in the early stages ... of infection • ... cells in the CNS ... disorder #dementia #AIDS ... #Neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Herpesviruses (MCC: HSV ... • Common clinical ... Altered mental status ... #diagnosis #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome - Overview ... • A state of hyperinflammatory ... /AIDS patients ... pleural effusions, CNS ... Differential #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Syndrome (PRES) Overview ... may precede the neurologic ... Seizures: Treat with AEDs ... Syndrome #diagnosis #management ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... response preceding infection ... Campylobacter jejuni - HIV ... • Weakness: Starts ... #treatment #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis Overview ... that results in CNS ... Transverse Myelitis - Clinical ... , HIV, Hep A/B/CMV ... #neurology #differential
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
iron overload states ... yeast • At risk: AIDS ... especially the CNS ... MC: CNS CSF: • ... Fungal #Diagnosis #Management