9 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Secondary prevention (statin ... #neurology #rheumatology ... cerebritis #diagnosis #management
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... in the early stages ... syndrome of HAD ... #dementia #AIDS ... #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... Suspect in movement disorders ... altered mental status
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... epilepticus Treatment ... Seizures: Treat with AEDs ... #diagnosis #management ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... COVID 19 - Zika virus ... • Weakness: Starts ... #diagnosis #management ... #treatment #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... Clinical Picture ... immunosuppressants - Meds ... Gravis #diagnosis #management ... #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
• A state of hyperinflammatory ... of HIV/AIDS patients ... be present: • AIDS ... pleural effusions, CNS ... Differential #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management ... #neurology #differential
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
iron overload states ... yeast • At risk: AIDS ... especially the CNS ... MC: CNS CSF: • ... Fungal #Diagnosis #Management