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hematology anticoagulant anticoagulation coagulation diagnosis noac oral apixaban bridging causes dabigatran dic direct disseminated edoxaban heparin inhibitor intravascular mechanisms medications
Coagulation Cascade and Anticoagulant Sites of Action - Amy Chung, MD, MSc https://twitter.com/AmyChung #AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... #Medications #Pharmacology ... #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet Novel (or Direct) Oral Anti-Coagulants • Rivaroxaban • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct ... #Oral #AntiCoagulant
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... #Oral #anticoagulant ... #hematology #management ... #pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... #Coagulation #Cascade ... platelet #thrombin #clot ... #pathophysiology ... anticoagulation #anticoagulant
Anticoagulant Bridging • Switching from LMWH • Switching from UFH • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from DOAC ... from Warfarin to DOAC ... anticoagulation #pharmacology ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... significant fibrin clot ... Reduction of pro/anticoagulants ... causes #treatment #management ... #hematology
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