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hematology differential causes workup agglutinin cold common cvid disease endocrinology gout hyperuricemia hypogammaglobulinemia immunodeficiency immunology macrocytic management microcytic naildisorders nonpalpable
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... Hypersplenism • Secondary ... #Algorithm #Causes ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Consider RBC membrane disorder ... #Diagnosis #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... #Causes #hematology ... #secondary
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Secondary Cold ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
- Differential Diagnosis ... Algorithm Primary ... Lymphoproliferative Disorders ... Leukemia (CML) - Hemolytic ... Anemia - Others
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... NailDisorders #Systemic #Secondary ... #dermatology #Differential ... #Diagnosis #Algorithm
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #nonpalpable #dermatology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... (BM) ablative disorders ... #Algorithm #Diagnosis ... #Workup #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... late adulthood • Diagnosis ... and autoimmune hemolytic ... anemia) • Systemic
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