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management hematology differential autoimmune chronic differentiation ekg electrocardiogram equivalents hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis ms multiple myopathy myositis neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... common • Imaging: CXR ... : >3 symptoms, or ... #APML #diagnosis
Pericarditis - Definition and Diagnostic Criteria Acute Pericarditis • Inflammatory pericardial syndrome to be diagnosed with
Inflammatory pericardial syndrome ... depression on ECG ... CMR). ... pericarditis and a symptom-free ... #criteria #cardiology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... lesions) McDonald diagnostic ... criteria for MS
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
STEMI Equivalents on ECG • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
segment at (or 40-60 ms ... point • De Winter syndrome ... V2 • Wellens sign ... #EKG #diagnosis ... #differential #cardiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... (e.g. incidental ... CXR finding) ... anterior/posterior MSK ... #Management #Signs
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Presentation • Common Signs ... and Symptoms: ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Management #Hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... muscle disease/muscular
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