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differential rheumatology management signs oncology causes spinalcord vasculitis acute algorithm apml arthritis autoimmune behcet central chronic classification cll cord differentiation
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... myositis overlap • Vascular ... #diagnosis #signs ... #workup
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... injury, often from vascular ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Vascular disorders ... (Wallenberg's syndrome ... Syndrome usually ... signs or symptoms ... #differential #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... common • Imaging: CXR ... : >3 symptoms, or ... #management #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... hypertension and signs ... renal bruit or signs ... Causes: • Vascular
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... and diplopia) • Vascular ... #signs #symptoms ... #rheumatology #
Heart failure with Reduced Ejection Fraction (HFrEF) Clinical Presentation 1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... un lymphatic Diagnostic ... of CXR congestion ... #management #cardiology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... Lack of UMN/LMN signs ... dystrophies Work ... #Differential #Diagnosis ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential Diagnosis ... and signs below ... Vascular/Blockage ... MCTD, Sjogren syndrome ... #neurology #differential
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