22 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Pathophysiology ... Cathepsin G release → vascular ... : >3 symptoms, or ... #management #hematology ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... and iron release Diagnosis ... functional ID) Treatment ... improvement in symptoms ... #management #cardiology
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
Pathophysiology: ... • Vascular smooth ... tests in cath lab Treatment ... Prinzmetal #Angina #cardiology ... #diagnosis #management
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
ophthalmoplegia), systemic signs ... and Workup: • ... No additional workup ... Imaging (if atypical symptoms ... #Management #Treatment
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
/Symptoms: • Usually ... be present or signs ... Pathophysiology: ... data • Early treatment ... #management
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... un lymphatic Diagnostic ... #heartfailure #diagnosis ... #management #cardiology
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
Signs: hypotension ... decreased ETCO2 Symptoms ... removal – consult vascular ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... microglobulin Treatment ... #workup #oncology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... 4) progressive muscular ... fasciculations Common Symptoms ... column Treatment ... #management