13 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... and Symptoms: ... Musculoskeletal: joint ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
valve lesions Abdominal ... pain (20%) Renal ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
cardiovascular system ... painAbdominal ... Positive Carnett's sign ... accompanied by joint ... #Pain #differential
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pain • Valgus ... position of knee ... pathophysiology #causes #symptoms ... #signs #diagnosis ... #msk
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Pain History ... or nerve root Symptoms ... osteopetrosis, avascular ... #Pain #MSK #rheumatology ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... #pain #Differential ... #Diagnosis #MSK
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... pulse deficits vascular ... pain • HTN • ... #Diagnosis #Rheumatology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... : cough, abdominal ... : weight gain, lung ... pulse pressure: systolic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
eruption - Joints ... - GI tract: abdominal ... Symptoms (Sx) in ... purpura: strong sign ... #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... and diplopia) • Vascular ... • Nonsurgical abdominal ... pain: Glucocorticoids ... #symptoms #rheumatology