15 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... phenomenon (20%) Joints ... lesions Abdominal pain ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... and Symptoms: ... Musculoskeletal: joint ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... #pain #Differential ... #Diagnosis #MSK
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pain • Valgus ... position of knee ... pathophysiology #causes #symptoms ... #signs #diagnosis ... #msk
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Fever/Chills/Joint ... pain/Night sweats ... Infection - Systemic ... arthritis - SLE ... #diagnosis #msk
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Pain History ... or nerve root Symptoms ... osteopetrosis, avascular ... #Pain #MSK #rheumatology ... approach #workup #differential
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
cardiovascular system ... patient is in the knee-to-chest ... Positive Carnett's sign ... accompanied by joint ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint ... pain • Swan neck ... Induced Lupus: • Symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... purpura: Strong sign ... pulse deficits vascular ... #Diagnosis #Rheumatology