14 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
(CVID, WAS), (neurologic ... changes), high MCV anemia ... not required in all ... or if a primary hematologic ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... respiratory failure • Neurologic ... loss of teeth • Muscular ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... (Thrombosis in vascular ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Cathepsin G release → vascular ... APML #diagnosis #management ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview: ALL ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... involve one, two, or all ... Out Secondary Causes ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology ... #oncology #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic complaints- anemia ... identifies 85 to 95% of cases ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management