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diagnosis differential bleeding classification antiphospholipid apls child cryoglobulinemia cryoglobulins dermatology glomerulonephritis hemostasis hypercoagulable limping monoclonal nwb oncology paraproteinemias pathway pediatrics
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... • Steroids • Vasculitis ... #Causes #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... sweats, pallor, bruising ... splenomegaly, abnormal neurology ... cell disease Rheumatology ... #Limping #NWB #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Disruptions in vascular ... (lupus, RA, Sjogren's ... • Abdominal ultrasound ... #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... and bullous or vesicular ... such as systemic lupus ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Vascular Sludging ... (e.g. systemic lupus ... classification #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... inhibitor and lupus ... discern these causes ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Vasculitis) Autoantibodies ... to cold IgG • Lupus ... (Thrombosis in vascular ... Paraproteinemias #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulse deficits vascular ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup Algorithm ... FOR TESTING: • Vascular ... maternal chromosomal causes ... excluded Testing: • Lupus ... #diagnosis #hematology
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