16 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Etiology: • Vascular ... Disruptions in vascular ... - GPA - EGPA ... Differential #Diagnosis #hematology ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... Cell Arteritis (GCA ... ANCA associated vasculitis ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Renal Disease Vascular ... • Steroids • Vasculitis ... #Causes #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Disruptions in vascular ... (lupus, RA, Sjogren's ... • Abdominal ultrasound ... #Causes #dermatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Is visual loss caused ... the optic nerve caused ... Doppler US : halo sign ... #Rheumatology # ... Ophthalmology #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... and branches • GCA ... such as systemic lupus ... purpura: strong sign ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Vascular Sludging ... (e.g. systemic lupus ... classification #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... with systemic, neurologic ... systemic sx + signs ... them, but urgent rheumatology ... #Temporal #Signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... pulse deficits vascular ... develop in pts with GCA ... tract, and often causes ... Differential #Diagnosis #Rheumatology