27 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Avascular necrosis ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... Non-bloody: OA, avascular ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology ... discrepancy, multiple joint
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
involving small joints ... shoulders Signs & Symptoms ... pain / swelling ... narrowing) • Ultrasound ... diagnosis #management #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... phenomenon (20%) Joints ... lesions Abdominal pain ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Pain History ... : Is the pain from ... or nerve root Symptoms ... osteopetrosis, avascular ... #Pain #MSK #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
constitutional symptoms ... Internal derangement/Avascular ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulse deficits vascular ... eruption • Joints ... • Progressive symptoms ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... and bullous or vesicular ... eruption - Joints ... Presentation - Systemic Symptoms ... differential #diagnosis #rheumatology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Chondrodysplasia Neurologic ... • Compensatory muscular ... Pain • Valgus ... pathophysiology #causes ... #symptoms #signs