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diagnosis differential algorithm classification dermatology erythematosus management sle systemic treatment acute aki ana antibodies antibody antineutrophil antinuclear aortitis bee bleeding
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... seen in 30—70% of cases ... Vasculitis: • ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Etiology: • Vascular ... Disruptions in vascular ... Cryoglobulinemia (MIXED) • ANCA ... Differential #Diagnosis #hematology ... #rheumatology #
Proposed treatment algorithm for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis #anca #vasculitis #treatment #algorithm #rheumatology #nephrology
cytoplasmic antibody (ANCA ... )-associated vasculitis ... #anca #vasculitis ... treatment #algorithm #rheumatology ... #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... and bullous or vesicular ... such as systemic lupus ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... Nodosa (PAN), ANCA ... associated vasculitis ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Intra-Renal: • Vascular ... Emboli, Thrombosis, Vasculitis ... • GN: ANCA, Anti-GBM ... Differential #Diagnosis #nephrology ... #causes #algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulse deficits vascular ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... Differential #Diagnosis #Rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Inflammatory causes ... syndrome • Systemic lupus ... spectrum disorder • ANCA-associated ... vasculitides • ... BEE #Syndromes #neurology
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