7 results
diagnosis hematology management signs aflp alkaline alp differential disease erythematosus essential et fatty hyophosphatasia joint leukemia liver low lupus musculoskeletal
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... #pathophysiology ... #signs #symptoms
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... other orthopedic complications ... Avascular necrosis ... differential #diagnosis #causes ... #hematology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... formation MSK ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms ... #complications
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
collection with EDTA Pathophysiology ... mineralization Symptoms ... loss of teeth • Muscular ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... = nonspecific (nausea ... Antithrombin Ill • Ultrasound ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... and complications ... 450,000/microL • Bone ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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