17 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
• Myopathy (Also ... caused by hydroxychloroquine ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... neoplasms) • Screen also ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... other orthopedic complications ... Avascular necrosis ... Hematogenous spread as ... #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential ... renal bruit or signs ... Causes: • Vascular ... #causes #Differential
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... : • Valvular disorders ... • Sepsis Complications ... #Diagnosis #Pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential ... #diagnosis #vascular
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
narrowing and vascular ... damaged BRB appears as ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms #complications
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Findings: • ↑AST/ALT ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Monitor and Treat Complications
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... bile ducts Differential ... cholangitis #diagnosis #workup
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... 4) progressive muscular ... Escorial criteria uses ... conditions listed in differential