18 results
Cutaneous Lupus Erythematosus
 • Acute Cutaneous Lupus (ACLE)
 • Neutrophilic Dermatoses 
 • Vascular Lesions
 •
Cutaneous Lupus ... Dermatoses • Vascular ... Erythematosus #diagnosis #types ... #venn #rheumatology ... #classification
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... S - Systemic Lupus ... #differential #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Vascular Sludging ... (e.g. systemic lupus ... #classification ... #rheumatology #
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... for ~3/4 of cases ... Accounts for <5% of cases ... VonWillebrand #Disease #Classification ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Non-autoimmune rheumatologic ... Kikuchi disease • Type-I ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Disruptions in vascular ... Autoimmune Vasculitis (lupus ... • Abdominal ultrasound ... #dermatology #physicalexam
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Establish hemophilia type ... Classify severity Treatment ... by a hemophilia treatment ... #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... Divided Into Two Types ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... hypertension and/or drug treatment ... neutropenia in collagen vascular ... neutropenia in collagen vascular ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
• Disorders of vascular ... inhibitor and lupus ... discern these causes ... Disruption in vascular ... Differential #Diagnosis #Hematology