23 results
diagnosis differential management algorithm classification pain anemia arthritis hemolytic hemophagocytic hlh lymphohistiocytosis msk oncology vasculitis workup antiphospholipid apls approach bleeding
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Spherocytes • Treatment ... transient hemolysis • Treatment ... Plasmapheresis - VA Joint ... Hemolytic #Anemia #hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... S - Systemic Lupus ... #differential #hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... spondyloarthropathies, lupus ... Non-bloody: OA, avascular ... Like in this case ... #rheumatology #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... idiopathic) - Autoimmune ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Avascular necrosis ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... hypertension and/or drug treatment ... neutropenia in collagen vascular ... neutropenia in collagen vascular ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
disease • Non-autoimmune ... rheumatologic diseases ... Arthritis: • Joint ... arthropathy • 90% joints ... Erythematosus #Diagnosis #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Autoimmune → Inflammation ... Internal derangement/Avascular ... weeks) Can Be Caused ... Rheumatologic Disease ... Diagnosis #MSK #rheumatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... presentation: Hepatic vascular ... steatosis • Autoimmune ... Diagnosis #Algorithm #hepatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Disruptions in vascular ... Palpable Rash: - Autoimmune ... Vasculitis (lupus ... • Abdominal ultrasound
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