21 results
diagnosis management differential syndrome arthritis disease msk oncology classification vasculitis acid algorithm alkaline alp apml approach autoimmune behcets bone capillary
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Avascular necrosis ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... Non-bloody: OA, avascular ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... neurology, back pain ... Haematology - ... cell disease Rheumatology ... discrepancy, multiple joint
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
involving small joints ... pain / swelling ... narrowing) • Ultrasound ... exam and imaging Treatment ... diagnosis #management #rheumatology
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... : Urine Common Uses ... diarrhea & abdominal pain ... #Indications #Pharmacology ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... Internal derangement/Avascular ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... immunosuppressive meds) Vascular ... #management #pharmacology ... #rheumatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
prematurely • risk of joint ... loss of teeth • Muscular ... (muscle/joint) ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Cathepsin G release → vascular ... effusions, weight gain ... Renal Failure Treatment ... diagnosis #management #hematology
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