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diagnosis nephrology causes pathophysiology antiarrhythmics cardiology classes medications table algorithm comparison diuresis diuretics druginduced effect excretion hypokalemia management phases properties
Vasopressors Table Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
properties by Target Receptor ... , Heart Rate/Inotropy ... - Dopamine, high ... Properties #Table #Pharmacology ... Management #Comparison #Inotropes
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Angiotensin II Receptor ... #differential # ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... Beta adrenergic receptor ... #differential # ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... Beta adrenergic receptor ... #differential # ... #high #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... (Vasopressin) ... bleeding disorders Vasopressin ... Diuresis #Nephrology #Pharmacology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... repolarization CLASS 3 - Potassium ... beta adrenergic receptors ... force (negative inotropy ... Vaughan #Williams #Pharmacology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... Hyperkalemic periodic ... #Differential # ... Diagnosis #High ... #Potassium #Classification
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... repolarization CLASS 3 - Potassium ... beta adrenergic receptors ... force (negative inotropy ... #Classification
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
urine Na/Cl < 0.7, high ... correcting serum potassium ... mineralocorticoid receptor ... and angiotensin receptor ... #diagnosis #differential
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