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Clinician's Pocket Guide to Vasopressors - Receptor Profiles and Hemodynamic Parameters
 • Systemic Vascular Resistance -
- Receptor Profiles ... Circulatory pressure • Inotropy ... #Pharmacology # ... comparison #table #receptors ... #inotropes
Receptor actions of sympathomimetic and dopaminergic agents.
Adrenaline (epinephrine) 
Noradrenaline (norepinephrine) 
Isoprenaline 
Dopamine 
Dopexamine 
Dobutamine 

#Pharmacology #Vasopressors
Receptor actions ... Dobutamine #Pharmacology ... #Vasopressors # ... Receptors #Targets ... Dopamine #Comparison #Inotropes
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... properties by Target Receptor ... , Heart Rate/Inotropy ... Properties #Table #Pharmacology ... Management #Comparison #Inotropes
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Vasopressors and ... Inotropes - Pharmacology ... Summary Vasopressors ... Dose dependent receptor ... #Inotropes #Pharmacology
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
dronedarone, dofetilide Vasopressors ... /inotropes - Epinephrine ... Medications #Causes #differential ... #diagnosis #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin II Receptor ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... beta adrenergic receptors ... force (negative inotropy ... Vaughan #Williams #Pharmacology ... #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... beta adrenergic receptors ... force (negative inotropy ... #Classification ... #Classes #pathophysiology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
• Heart - ↑ Inotropy ... Chronotropy and inotropy ... Adrenoceptor #adrenergic #receptors ... #actions #pharmacology ... #pathophysiology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... administration, vasopressors ... , or inotropes ... Acidosis #Elevation #Differential ... #typea #typeb #classification