10 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Associated - SLE ... #Diagnosis #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... Leucopenia/lymphopenia, Thrombocytopenia ... erythematosus #signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... Neurological 12% - Thrombocytopenia ... Lupusreference #SLE ... autoantibodies #signs ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... hemostasis: - Thrombocytopenia ... Disruptions in vascular ... deficiency Work ... #Differential #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behcet disease) Differential ... Oral aphthae : SLE ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... Neutropenia, anemia, thrombocytopenia ... Leukemia #diagnosis #workup ... #oncology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... erythematosus [SLE ... leukopenia, anemia, and thrombocytopenia ... #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... and bullous or vesicular ... mucositis - Rash ... purpura: strong sign ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... purpura: Strong sign ... and bullous or vesicular ... , mucositis • Rash
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
erythematosus (SLE ... along with (VEGF) vascular ... TAFRO #diagnosis #management ... #rheumatology # ... Thrombocytopenia