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rheumatology classification differential criteria disease erythematosus management signs sle symptoms systemic arteritis behcet behcets cryofibrinogenemia cryoglobulinemia cryoglobulins eularacr gca giantcell
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... least 2 joints • Neurologic ... pericarditis • Hematologic ... Erythematosus #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... inflammation Others: • Lupus ... such as systemic lupus ... • Complement (Low ... #rheumatology #
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... Uveitis or retinal vasculitis ... test Most Common Clinical ... oligoarticular, medium-large ... #criteria #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low ... Differential Diagnosis ... Clinical Features ... , lymphopenia, low
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... Labs/Diagnosis: ... factor level • Low ... (e.g. systemic lupus ... Cryoglobulins #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... Medium and large ... (Clinical Dx). ... signs #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... affects the skin, neurologic ... cognitive impairment, neurologic ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Vasculitis) Autoantibodies ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... pulmonary emboli, and ocular ... : • + Clinical ... Antiphospholipid syndrome ... hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... with systemic, neurologic ... Involves large and medium ... Diagnosis = clinical ... = vasculitis vs
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