11 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Syndrome: Distal ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
: Proximal and distal ... SAME, Cushing Syndrome ... diuretics, Bartter syndrome ... , Gitelman syndrom ... potassium #low #nephrology
Continuous B-cell depletion in frequently relapsing, steroid-dependent and steroid-resistant nephrotic syndrome 

Clinical Kidney Journal, , sfy067,
steroid-resistant nephrotic syndrome ... complicated nephrotic syndrome ... - Visual Abstract ... NephroticSyndrome #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
ascending limb Gitelman ... cotransporter in distal ... tubule Liddle syndrome ... mineralocorticoid receptor Distal ... Defects #Kidney #Nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
↓ Aldosterone: Syndrome ... excess, Liddle's syndrome ... , Gitelman syndrome ... Proximal RTA, Distal ... differential #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... of cells on the distal ... #nephrology #management ... #pathophysiology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Aldosterone: Cushing syndrome ... excess, Liddle syndrome ... Proximal RTA • Distal ... , Gitelman syndrome ... algorithm #diagnosis #nephrology
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
disconnection syndrome ... Visual information ... Pathophysiology: ... Agraphia #clinical #neurology ... #diagnosis #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... mental status • Visual ... may precede the neurologic ... Etiology: • Pathophysiology ... diagnosis #management #neurology