8 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... : Proximal and distal ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... Bartter syndrome, Gitelman ... Proximal RTA, Distal ... #differential # ... potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... of cells on the distal ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Bartter syndrome, Gitelman ... settings, the urine sodium ... the excretion of sodium ... #nephrology #differential
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... with hypokalemia ... Bartter syndrome, Gitelman ... urine #potassium #differential ... #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Diagnosis Algorithm ... excretion (GFR, TTKG, distal ... Non-Anion Gap Metabolic ... IntercellularShift #Nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
mental status • Visual ... Blood transfusion, Hypercalcemia ... narrowing on MRA/CTA ... Reversible course Differential ... Drug toxicity, Metabolic