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differential management algorithm anemia cold erythematosus hematology hemolytic lupus manifestations ms multiple myelitis neuromyelitis nmo optica polychondritis relapsing sclerosis signs
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Agglutinin Disease ... Agglutinin Syndrome ... chills, flank pain ... #agglutinin #disease
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
neuritis: Reduced visual ... • Extra-CNS complications ... disorders (Systemic ... Manifestations #diagnosis ... #neurology #symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... MCTD, Sjogren syndrome ... #diagnosis #neurology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Non-autoimmune ... rheumatologic diseases ... Arthritis: • Joint pain ... Induced Lupus: • Symptoms ... #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... or without back pain ... Bilateral signs and/or symptoms ... Evaluate for NMO, SLE ... #management #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Sclerosis (MS) is an autoimmune-mediated ... neurodegenerative disease ... • Or brainstem syndromes ... impairment, Mood disorder ... Sensitivity to pain
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... Presentation: Systemic Symptoms ... claudication, visual ... • Progressive symptoms ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... disorder) Who ... Sudden onset of pain ... cases such as: • SLE ... Polychondritis #rheumatology
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