11 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... and/or joint aches ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
bacterial, fungal, or viral ... #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Arthritis: • Joint ... pain • Swan neck ... #Diagnosis #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... the face (many differential ... clues #system #erythematosus ... #rheumatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
vomiting, abdominal pain ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral ... #obstetrics #obgyn
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... level to exclude myositis ... low back pain) ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... vesicular eruption - Joints ... systemic lupus erythematosus ... LFT • ESR • ANA ... #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... lesions • Severe pain ... deficiency Work ... • Abdominal ultrasound ... #Diagnosis #Algorithm
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
claudication, visual ... ischemia • Skin: Erythematous ... tract: Abdominal pain ... Palpable purpura, joint ... #Diagnosis #Rheumatology