14 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
ejection fraction, treatment ... cardiovascular causes ... - Visual Abstract ... Spironolactone #HFpEF #dCHF
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Usual maintenance ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Na delivery): CHF ... 20 suggests ↓ distal ... only if no clear cause ... Elimination (see Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... - Infection - Viral ... Treatment of underlying ... per day until stable ... Diagnosis #Management #causes
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
psychosis - CHF ... ↑ T3 - Mild hypercalcemia ... ↑ AST/ALT • Treatment ... diplopia, change in visual ... hyperthyroidism #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
ETOH Infection (Viral ... per day until stable ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
effects in the treatment ... skin reactions, visual ... valleyfever #management #treatment ... antifungals #comparison #table ... #pharmacology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
mental status • Visual ... Blood transfusion, Hypercalcemia ... the underlying cause ... • Treatment of ... with AEDs until cause
Randomized Controlled Trial of Intravenous Acetaminophen Versus Intravenous Hydromorphone for the Treatment of Acute Pain in
Hydromorphone for the Treatment ... the cost of more nausea ... and vomiting Visual ... Abstract by David ... VisualAbstract #Pain #Pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
ECG is vital while ... the determined cause ... #table #foamed ... #heartfailure #chf ... icu #clinical #pharmacology