11 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... #management #treatment ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Marrow (Toxic injury ... • ↓ WBC • ↓ ... #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... aplasia • ITP ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Vmphocytosis on routine CBC ... marrow failure with anemia ... uw_IMresidency #CLL ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
The underlying pathophysiology ... ischaemia. 2) Aplasia ... of the baseline anaemia ... Crisis #Features #Signs ... #Symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... systemic complaints- anemia ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... ingestion • B symptoms ... platelets - WBC ... classification #hematology ... #oncology #management
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
) Acute kidney injury ... microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... injury, arteriolar ... of arteries Management