74 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
malignancy: • Symptoms ... : B-symptoms, bruising ... hepatomegaly • Labs: anemia ... platelets, persistent WBC ... Algorithm #hematology #WBC
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Iron-deficiency anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... coagulopathy (DIC) #RBC
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... • Improve the symptoms
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Neutrophils - Low RBC ... • Pernicious Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
experience some symptoms ... RBC are produced ... Approximately 1% of RBC ... destruction of RBC ... Mentzer index = (MCV/RBC
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Dehydration • Symptoms ... changes, stroke symptoms ... • Lab values: WBC ... tumor burden • Symptoms
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. 

Source:  Does This
Acute Coronary Syndrome ... Likelihood Ratios for Symptoms ... Acute Coronary Syndrome ... EBM #Diagnosis #Cardiology ... AcuteCoronarySyndrome #Symptoms
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Hepatorenal syndrome ... Hepatoadrenal syndrome ... Hepatopulmonary syndrome ... suppression, Anemia ... failure #Signs #Symptoms
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... Serum PO4 -> decr RBC ... hemolysis - anemia ... pathophysiology #symptoms
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Drug-associated, PCH, Evans Syndrome ... 3) Internal (RBC ... Defects: Sickle cell anemia