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causes hemolytic hemolysis workup approach atlas bloodcell elevatedmcv extravascular hodgkins intravascular lymphoma macrocytic macrocytosis microscopy morphology nomenclature oncology platelet red
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Blood Loss ... #Classification ... #Diagnosis #Algorithm ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease ... Agglutinin Syndrome ... anemia • Cold ... smear - RBC agglutination ... #hematology #diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , McLeod blood group ... Unstable hemoglobin disorders ... #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Normal Blood Smear ... Neutrophils - Low RBC ... #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... agglutinins disease ... hypertension • Unusual RBC ... Diagnosis #Algorithm ... #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Autoimmune: Warm AIHA, Cold ... 3) Internal (RBC ... - Peripheral Blood ... #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
agglutin disease ... lymphoproliferative disorders ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... plateletcount), peripheral blood ... changes), high MCV anemia ... ), HBsAg/anti-HBc ... #Workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... platelets - WBC ... number of sites of disease ... #hematology #oncology ... #management
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