9 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Normal Blood Smear ... • Drugs Oval Macrocytes ... Myelodysplastic Syndromes ... #Macrocytic ... #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Microcytic RBC: ... (sometimes) Macrocytic ... , McLeod blood group ... #microscopy #atlas
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... 95 (or 100) is macrocytic ... in peripheral blood ... High in acute blood ... #Workup #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Lead poisoning • Macrocytic ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... #differential #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... Abnormalities: macrocytic ... anemia, thrombocytopenia ... including peripheral blood ... #Somatic #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... hematologic: Acute blood ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Myeloproliferative Disease ... Workup: • Complete ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... cells can indicate disease ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... Leukemia #diagnosis #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... the presence of anemia ... : • Complete blood ... count (CBC) •