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diagnosis management clinical differential algorithm signs symptoms cardiology hematology causes pharmacology nephrology syndrome pocus endocrinology treatment workup pulmonary ophthalmology hepatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... Even with normal WBC ... cultures, including blood ... 21% had normal WBC ... #pathophysiology
Septic Arthritis: Pathogenesis and clinical findings Notes: - Septic Arthritis is typically monoarticular & the knee is involved
cases - decr blood ... clarity, >50000 WBC ... SepticArthritis #pathophysiology
Pathogenesis of meningitis Risk factors for pathogen entry include immunocompromised state (HIV positive, cancer, chemotherapy patients,
changes in the blood ... increases white blood ... cell (WBC) binding ... #Meningitis #Pathophysiology
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
as a result of WBC ... Decreased insulin in blood ... the decreased blood ... #DiabeticFoot #pathophysiology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Diarrhea (>3 BM/d) ± blood ... pain, Fever, ↑WBC ... Perforation) Pathophysiology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... Life Whole blood ... WBC and platelets ... Hct 35%. 450mL blood ... X 1010); some WBC
Urine Microscopy and Casts - Image Atlas Key - Squamous Epithelial Casts - Transitional Epithelial Cells - Renal Tubular
Hyaline Cast - WBCs ... Granular Casts - WBC ... Cast - RBC Cast
Arthrocentesis - Synovial Fluid Analysis Normal < 150 WBC, Colorless/Straw color, High Viscosity Noninflammatory < 3,000 WBC, Straw/yellow
Analysis Normal < 150 WBC ... Noninflammatory < 3,000 WBC ... Inflammatory > 3,000 WBC ... purulent) > 50,000 WBC ... similar to blood
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
defined as white blood ... Mature WBC: 80- ... in peripheral blood ... the margins of blood ... ) and immature WBCs
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Alwavs Repeat Blood ... while drawing blood ... ischemia-induced RBC ... hemolysis) • RBC ... potassium #high #pathophysiology
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