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hematology causes hemolysis agglutinin atlas classification cold differentiation disease hodgkins key lymphoma morphology rbc syndrome thromboticthrombocytopenicpurpura ttp workup
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... Diagnosis Algorithm ... Extravascular ... elliptocytosis - RBC ... Differential #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... • Intrinsic RBC ... #Hemolytic #Intravascular ... #Extravascular ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... , Disseminated intravascular ... coagulopathy (DIC) #RBC ... Morphology #Atlas #key #diagnosis ... #differential #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... QD until normal WBC ... #diagnosis #management ... #hematology #oncology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
reflection of intravascular ... anemia Indirect ... from ischemia WBC ... count and differential ... #Workup #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Blood smear - RBC ... younger pts) Differential ... the RBCs causing intravascular ... #anemia #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... anemia • Pain ... platelets - WBC ... Immunohistochemical studies (to differentiate ... #oncology #management
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