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differential causes oncology systemic dermatology generalized leukemia pruritus agglutinin aplastic classification cll cold disease disorders elevatedmcv erythematosus hemolytic lupus lymphocytic
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
WBCs - Decreased ... Hypersplenism • Secondary ... RA, SLE, PRV, Chronic ... Reticulocytosis • Renal ... #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... (+) ↑ WBC ... #Disorders #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Algorithm Decreased ... Deficiency (Eg Causes: Chronic ... Blood Loss, Occult ... Secondary to Inflammation ... #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
/ Systemic == Blood ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Algorithm Blood ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Myelodisplastic syndrome ... #Pruritus #secondary
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• ↓ WBC • ↓ ... • Improve the symptoms ... result from low blood ... #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Cold Agglutinin Syndrome ... smear - RBC agglutination ... sensitize red blood ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... cell count (anemia ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... workup #oncology #hematology
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