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diagnosis differential management algorithm anemia aplastic bruising cirrhosis cll dic diffuse disseminated globulin hemostasis hepatopulmonary hps intravascular lad lymphadenopathy lymphocytic
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - History of Bleeding ... (Pancytopenia, WBC ... Age > 50 • Chronic ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... activity • ↓ LAP ... -> AML: Blast crises ... • Tumor lysis syndrome ... #Hematology #Oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... DIC • Severe Liver ... hydration • RBC ... treatment #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... #hematology #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
gingivitis or gingival leukemic ... inhibitor of a coagulation ... von Willebrand syndrome ... discern these causes ... Differential #Diagnosis #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... differential #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
triad of: 1) chronic ... dilatation & 3) gas ... arteriovenous shunting causes ... of orthodeoxia CLINICAL ... cirrhosis #diagnosis #hepatology
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