16 results
anemia differential chronic hemolytic intravascular lymphocytic mds myelodysplastic treatment agglutinin algorithm aplastic cancer classification cold common cvid dic differentiation disseminated
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... extramedullary disease ... -> AML: Blast crises ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Diagnosis: • ... can indicate disease ... adult T cell leukemia ... #oncology #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
marrow plasma cell ... , B and T cell lymphoproliferative ... diseases, CML, ... plasmacytoma, POEMs syndrome ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute leukemia ... Allogeneic stem cell ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... Transformation to large cell ... uw_IMresidency #CLL ... #oncology #hematology ... #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation ... ) (e.g. lupus, CLL ... Hemoglobinopathies (e.g. sickle cell ... #hematology #anemia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... #APML #diagnosis ... #management #hematology ... #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoid malignancy (CLL ... malignancies - B-cell ... malignancies -> CLL ... significance (MGUS), CLL ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... Cell Leukemia ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... +Organomegaly+↑RBC ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
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