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diagnosis hematology oncology differential algorithm classification management rheumatology workup causes chronic cll diffuse disorders erythematosus lad leukemia lupus lymphadenopathy lymphocytic
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Hodgkin Lymphoma ... Lymphoma - Clinical ... platelets - WBC ... classification #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Reactive: - Systemic ... Inflammatory • Systemic ... (Pancytopenia, WBC ... Cells on Biopsy ... • Hodgkin's
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... identical to the non-Hodgkin ... Orange or Hep C Clinical ... Lymphocytosis on CBC ... Scoring system:
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm Hodgkin ... site in lymphatic system ... with lymphatic system ... Depletion Non-Hodgkin ... pathophysiology #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... ducts Clinical ... Malignancy Risk: • Non-Hodgkins ... lymphoma • B cell ... B cell lymphoma
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... (HCV) • CLL & ... Marginal zone lymphoma ... +Organomegaly+↑RBC ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Angioimmunoblastic T-cell ... lymphoma • Evans ... : • Chronic B-cell ... cyclophosphamide) • Hodgkin
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • CBC + diff • ... macroglobulinemia • Non-Hodgkin ... Lymphoma (NHL) ... Diagnosis #Workup #Hematology
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