12 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... hemolytic anemia) • Systemic ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Caused by intrapulmonary ... shunt (Type 2) Clinical ... Arterial blood gas (ABC ... #treatment #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... • Severe Liver Disease ... hydration • RBC ... #treatment #management ... #hematology