19 results
diagnosis hematology differential management algorithm secondary dermatology generalized leukemia mds monoclonal pruritus systemic aplastic apml atlas chronic cirrhosis classification cll
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... Cells, Normal WBCs ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... old, ~10,000 new cases ... cytopenias (usually anemia ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age • 22 and 45 cases ... skin that are caused ... Out Secondary Causes ... #hematology #oncology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Liver diseases, Myelodysplastic ... syndrome, Increased ... Hemolytic uremic syndrome ... #differential #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Hypocellular myelodysplastic ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... #hematology #secondary
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... Hypothyroidism, Myelodysplastic ... syndrome - Dr ... differential #diagnosis #causes ... #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... renal failure/uremia ... Hyperthyroidism CBC ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... • Intrinsic RBC ... #anemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... : • Pathophysiology
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