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management algorithm hemolysis hemolytic atlas bandemia causes cbc cholangitis chronic classification differentiation extravascular gap globulin hepatitis hodgkins injury intravascular key
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... Pathophysiology ... bile ducts Differential ... #Cirrhosis #PBC ... #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... #APML #diagnosis ... #management #hematology ... #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... Consider sickle cell ... #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... - MAHA: TTP, HUS ... Drug-associated, PCH, Evans Syndrome ... anemia, Thalassemias ... #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (HUS) • Other ... ) (e.g. lupus, CLL ... Extravascular #Causes #differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... hepatitis: < 1 • Cirrhosis ... #hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary ... Syndrome - Diagnosis ... with or without cirrhosis ... #syndrome #diagnosis ... management #treatment #hepatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
population has ... • Autoimmune diseases ... #differential # ... #WBC #CBC #hematology ... #pathophysiology
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