14 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
of Thrombotic Thrombocytopenic ... Purpura (TTP) Diagnosis ... Contraindication to platelets transfusion ... #Purpura #management ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... TMA: Unexplained thrombocytopenia ... Initial labs: CBC ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... HUS) • Other: Transfusion ... • Intrinsic RBC ... #hematology #anemia
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Hemolytic anemia, Post transfusion ... Thrombotic idiopathic thrombocytopenia ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Volume Reduced RBC ... • Washed RBC ... purpura & severe thrombocytopenia ... #diagnosis #management ... #hematology #reactions
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
hydration • RBC ... transfusion for ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Non-Hemolytic Transfusion ... purpura & severe thrombocytopenia ... #diagnosis #management ... #hematology #reactions
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if high risk if WBC ... opacities • Diagnosis ... QD until normal WBC ... #management #hematology ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Diuretics, PRBC transfusion ... • Lab values: WBC ... Syndrome #TLS #diagnosis ... #management #hematology