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differential anemia blood causes chronic cll leukemia lymphocytic product reactions syndrome treatment ttp workup algorithm aplastic apml atlas classification coagulation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... HUS) • Other: Transfusion ... • Intrinsic RBC ... #hematology #anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Hemolytic anemia, Post transfusion ... Thrombotic idiopathic thrombocytopenia ... , Disseminated intravascular ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... transfusion for ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
of Thrombotic Thrombocytopenic ... Purpura (TTP) Diagnosis ... Contraindication to platelets transfusion ... #Purpura #management ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... TMA: Unexplained thrombocytopenia ... Initial labs: CBC ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Volume Reduced RBC ... • Washed RBC ... purpura & severe thrombocytopenia ... #diagnosis #management ... #hematology #reactions
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Non-Hemolytic Transfusion ... purpura & severe thrombocytopenia ... #diagnosis #management ... #hematology #reactions
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... activity is the diagnostic ... reflection of intravascular ... from ischemia WBC ... #Workup #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
if high risk if WBC ... opacities • Diagnosis ... QD until normal WBC ... #management #hematology ... #oncology
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