WBC pathophysiology diagnosis causes signs algorithm hepatology complications syndrome anemia cirrhosis dermatology elevatedmcv primary

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12 results

Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

Causes of Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... #Algorithm #Causes ... #Hematology

Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI

Causes of Anemia ... WBCs - Decreased ... Reticulocytosis • Primary ... #Algorithm #Causes ... #Hematology

Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or

Causes of Anemia ... Algorithm Decreased ... #Macrocytosis #elevatedMCV ... #Algorithm #Causes ... #Hematology

Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
• Artifact (redo CBC)
Autonomous:
• Essential thrombocytosis
• Polycythemia

Artifact (redo CBC ... Myelogenous Leukemia • Primary ... Iron deficiency anemia ... #Algorithm #Causes ... #Hematology

Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
• Female:Male 9:1
• Common European descent
• Age:

Cirrhosis (PBC) ... Pathophysiology ... intralobular bile ducts causes ... Signs and Symptoms ... #hepatology

Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /

Algorithm - Systemic ... and Primary Causes ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... Extravascular Causes ... usually IgM) (e.g. primary ... • Intrinsic RBC ... #hematology #anemia

Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
• Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity

blasts and high WBC ... count cause hyperviscosity ... >100k, + lab signs ... #TLS #diagnosis ... #management #hematology

Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
• Diabetes Mellitus
Liver Function Tests/Enzymes:

Pruritus - No Primary ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

Physical Exam/Signs ... Lymphocytosis on CBC ... • Neutropenia, anemia ... • Richter’s Syndrome ... workup #oncology #hematology

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