17 results
diagnosis oncology anemia differential treatment causes chronic cll hemeonc heparin hit induced intravascular leukemia lymphocytic rheumatology activation agglutinin algorithm aplastic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... uremic syndrome ... usually IgM) (e.g. primary ... • Intrinsic RBC ... differential #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... spherocytosis, Hemolytic ... uremic syndrome ... Thrombotic idiopathic thrombocytopenia ... #differential #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/Quantity: • Primary ... DIC/TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... • Lab values: WBC ... TLS #diagnosis #management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... Treatment: • Treat primary ... causes #treatment #management ... #hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
diagnosis and initial management ... approach is based primarily ... on clinical assessment ... #Hematology #HIT ... Heparin #Induced #Thrombocytopenia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... Blood smear - RBC ... #anemia #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... #Treatment #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... infections/fevers • Thrombocytopenia ... • ↓ WBC • ↓ ... Anemia #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... if high risk if WBC ... APML #diagnosis #management ... #hematology #oncology
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