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rheumatology leukemia lupus workup chronic erythematosus lymphocytic signs syndrome thrombocytopenia treatment aplastic arteritis arthritis centralretinalartery cerebritis classification cns common comparison
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... months to years) Systemic ... : Chronic disease ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Causes: - Idiopathic ... , breast CA - Hematologic ... - CBC may also ... #dermatology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment
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