452 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... • Lab values: WBC ... : • Pathophysiology ... TLS #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... if high risk if WBC ... QD until normal WBC ... APML #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... Miller Fisher Syndrome ... - NORMAL CSF WBC ... #diagnosis #management
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct of 70-80% - RBC ... X 1010); some WBC ... X 1011); some WBC ... Volume #Hematology #Management
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... glomerular hematuria (RBC ... Nephritic #Nephrotic #Syndrome
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology ... - Defects in RBC ... - Defects in RBC ... environment #Pathophysiology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... Nephritic #Nephrotic #Syndromes
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel Syndrome ... (IBS) - Pathophysiology ... Diagnosis and Management ... #Pathophysiology ... #Diagnosis #Management
Pathophysiology of hepatorenal syndrome (HRS)

doi: 10.1136/bmj.m2687 

#hepatorenal #syndrome #HRS #Pathophysiology #nephrology
Pathophysiology ... of hepatorenal syndrome ... #hepatorenal #syndrome ... #HRS #Pathophysiology
Inherited Colorectal Cancer (CRS) Syndromes
Adenomatous Polyposis Syndromes:
 • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Colorectal Cancer (CRS) Syndromes ... Adenomatous Polyposis Syndromes ... Urinary → Lynch Syndrome ... Peutz-Jeghers Syndrome ... #diagnosis #management