31 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... Neutrophils - Low RBC ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... coagulopathy (DIC) #RBC ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #generalized #dermatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Defects, Drugs, Liver ... 3) Internal (RBC ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #generalized #dermatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Diagnosis Framework ... Spherocytosis, G6PD, PK, HbC ... Non-megaloblastic: Liver ... #Diagnosis #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... #WBC #CBC #hematology ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... cholestasis → Cirrhosis/Liver ... asymptomatic • Pruritus ... or higher • Liver ... bile ducts Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management