96 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... glomerular hematuria (RBC ... casts or dysmorphic ... RBCs in urine)?
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... urine sediment - WBC ... /RBC casts ... Diagnosis #Algorithm #Causes
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... Nephritic #Nephrotic #Syndromes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria: 3 or more RBC ... disease - Alport syndrome ... pain hematuria syndrome ... hematuria: - RBC ... - Dysmorphic RBC
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Acellular Casts ... • Hyaline Casts ... suggestive of nephrotic sydnrome ... : • RBC Casts - ... glomerulonephritis • WBC
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Neutrophils - Low RBC ... Pernicious Anemia RBCs ... Myelodysplastic Syndromes ... Cells, Normal WBCs
Knee Effusions - Arthrocentesis Interpretation

Inflammatory arthritis:
 • Color: Yellow-> Green
 • Clarity: Opaque
 • Viscosity: Low
Knee Effusions - ... Viscosity: Low • WBC ... : Variable • WBC ... Viscosity: High • WBC ... analysis: • MSU
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... stone, Malignancy, PBC ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... TLS #diagnosis #management
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Osteoarthritis - Overuse syndrome ... Seronegative Reactive Syndrome ... #causes #differential ... #diagnosis #msk